Unilateral leg pain can happen in some conditions like diabetes where the nerves are affected. It can also be seen in conditions where the nerves are directly affected, nerves which move down from the spinal cord to the lungs. So any compression or irritation to the nerve at any point can cause a pain in the leg on that particular side. In children it is very common to see the leg pain because of the growth of the bones. It can be unilateral or bilateral. In menopause women do complain of unilateral leg pain. Any condition affecting the artery or the vein where the circulation is affected then that can cause leg pain. If the veins are not able to take the blood across it because of a clot or because it is dilated too much as in varicose veins then that also can cause unilateral leg pains.
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