We can divide abdomen with 4 imaginary quadrant.
Following organs are located In the Right lower quadrant:
appendix, the upper portion of the colon, and the right ovary and the Fallopian tube in women.
Generally, abdominal pain is common and most cases are mild, without any serious underlying cause.
In Most cases abdominal pain is caused by indigestion, gas, constipation, muscle spasm, muscle strain or gastritis.
But when pain is severe and located, specifically on right lower quadrant of abdomen, then most common cause is appendicitis.
Appendicitis is inflammation of the appendix. Appendix is a part of intestine.
Treatment of appendicitis surgical removal of appendix and it is called appendectomy.
Appendectomy is the most common surgical operation of abdomen.
Appendicitis has its highest incidence between the ages of 10 and 30 years.
Untreated, appendicitis can lead to perforation of the appendix, which typically occurs within 24 to 36 hours of the onset of symptoms. Perforation of the appendix can cause intra-abdominal infection, sepsis, intraperitoneal abscesses, and rarely death.
In order to avoid the sequelae of perforated appendicitis, a low percentage of “negative” appendectomies is generally accepted from a surgical standpoint.
If we suspect appendicitis surgical consultation should be provided, without any delay.
And we can suspect on appendicitis with the following symptoms:
abdominal pain migrating to the right lower quadrant (RLQ),
Pain from appendicitis may begin as dull pain around the navel. After several hours, pain will usually transition towards the right lower quadrant, where it becomes localized.
anorexia, fever, and nausea/vomiting. On examination, RLQ tenderness (hard), along with “classical” signs of peritoneal irritation (e.g., rebound tenderness, guarding, rigidity, referred pain).

Rebound tenderness, also known as Blumberg’s sign, refers to the presence of pain when pressure is removed from the abdomen, rather than when applied.
Abdominal guarding is the tensing of the abdominal wall muscles to guard inflamed organs within the abdomen from the pain of pressure upon them. The tensing is detected when the abdominal wall is pressed.
although many patents can have atypical presentation, so appendicitis can possible partial or without abomination symptoms.
Imaging tests, such as ultrasound (US), computed tomography (CT) with and without contrast, and magnetic resonance imaging (MRI), are also used extensively for the diagnosis of appendicitis.

Among Women, other serious causes of lower right abdominal pain can be ovarian cyst rupture, or adnexal torsion.
Other causes can be: Kidney stones, kidney infection, hernia, rarely, inflammatory bowel disease (IBD),
irritable bowel syndrome (IBS).

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Appendicitis is the most common cause of right lower abdominal pain requiring surgery.
The pain from appendicitis typically starts near the navel and shifts to the right lower abdomen, becoming sharper over time.
Increased pain with coughing, movement, or jarring activities is a key indicator of appendicitis.
Young people and teens are more prone to appendicitis, often due to a blockage by stool.
Over 80% of appendicitis cases necessitate surgical intervention to prevent life-threatening complications like peritonitis.
Diagnostic tests for appendicitis include ultrasound and CT scans, with Rovsing’s sign and rebound tenderness being clinical indicators.
Kidney stones are another major cause, characterized by severe pain starting from the back or side and potentially moving towards the groin.
The pain from kidney stones is often described as the worst imaginable and is significantly different from that of appendicitis.
Ovarian cysts, fluid-filled sacs on or in the ovaries, can cause a dull ache or sharp pain, especially upon rupture.
Gastroenteritis, or stomach flu, leads to crampy, diffuse pain and is accompanied by symptoms like bloating, diarrhea, and vomiting.
Irritable Bowel Syndrome (IBS) typically causes chronic discomfort and pain, not specifically in the lower right abdomen but possible.
Inflammatory Bowel Disease (IBD) includes conditions like Crohn’s disease, which often causes pain in the lower right abdomen.
Anti-inflammatory medications are commonly used for IBD treatment, with surgery as an option in severe cases.
Additional causes of lower right abdominal pain include endometriosis, pelvic floor dysfunction, ectopic pregnancy, diverticulitis, and intestinal herniation.
The majority of conditions causing lower right abdominal pain require medical diagnosis and treatment, highlighting the importance of professional evaluation.

Disclaimer:

This information is provided for general knowledge and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor for any questions or concerns you may have about your health.

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